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News & Press Releases

Fecal Microbiota Transplantation: What We Know and What We Need to Know »
Editorial from Dr. Christina Surawicz. The excitement about FMT is justified given its high efficacy in treating recurrent CDI, relative availability and simplicity, and favorable cost profile compared with other therapies. FMT also gives us insight into the importance of the gut microbiota in maintaining health and the therapeutic potential therein.
Annals of Internal Medicine. May 2015.
A New Less-Than-Expected Gastrointestinal Treatment »
Seattle Magazine features Drs. Christina Surawicz and Elizabeth Broussard and their work with stool transplants (fecal microbiota transplantation) for treating patients suffering from Clostridium difficile.
Seattle Magazine. April 2015.
Putting Together The Puzzle: Pancreatic Cancer »
RadioLab follows Dr. Teresa Brentnall's decade-long race to discover the source of familial pancreatic cancer. Listen to the story of Family X and the road to announcing a powerful discovery.
RadioLab. April 2015.
Polymerase Slippage Restoration of Frameshifted TGFBR2 in
Colorectal Cancer: A Novel Paradigm »

Editorial from Dr. William Grady. The demonstration of RNA polymerase slippage in CRC is an aspect of a recent study that deserves special attention. Polymerase slippage has been observed in model organisms and in other contexts, but the findings in this study demonstrate that this can also occur in human cancer cells.
Gastroenterology. April 2015.
The Impact of Racial and Ethnic Differences in Inflammatory Bowel Disease Phenotype in the United States »
Expert opinion from Dr. Anita Afzali. IBD has become a global disease with a rising incidence in both developed and developing countries. There are racial differences in IBD phenotype in the adult population in the US. These differences have implications in the diagnosis, management, and treatment of disease as well as complications of disease.
e-WGN (World Gastroenterology News). April 2015.
Drs. Rahul Kuver & Charles Landis Receive UWMC PRAISE Awards »
Drs. Rahul Kuver and Charles Landis have received 2015 UWMC PRAISE (Patient Reported Assessment in Satisfaction and Excellence) Awards. This award is given biannually to physicians ranking top in the nation for their excellent communication with patients. Dr. Landis is a two-time recipient. He and Dr. Anita Afzali received HMC PRAISE Awards in July 2014. Congratulations to all our physicians. We are honored to receive such generous support from our patients.
DOM Week. April 2015.
Trends in Hospitalization for Diverticulitis and Diverticular Bleeding
in the United States From 2000 to 2010 »

Study results from Dr. Lisa Strate. Complications of diverticular disease are the leading gastrointestinal indication for hospital admission in the US. In 2009, an estimated 280,000 individuals were hospitalized for diverticular complications in the US at an aggregate cost of $2.7 billion.
Clinical Gastroenterology & Hepatology. April 2015.
Hepatocyte Transplantation:
A Potential Treatment for Radiation-Induced Liver Damage »

Study results from Dr. Charles Landis. Radiation-induced liver damage (RILD) is a poorly understood and potentially devastating complication of hepatic radiation therapy for liver cancers. Previous work has demonstrated that hepatocyte transplantation can ameliorate RILD in rats.
Liver International. April 2015.
Dr. Peter Liang Receives 2015 Fellowship2Leadership Award »
This is a competitive award given to 35 GI Fellows each year. The overall goal of this travel grant program is to facilitate the continued growth and development of 2nd- and 3rd-year gastroenterology and hepatology fellows who have demonstrated the ability and initiative to be future leaders in their field. This is the third year that our program has had a winner.
Unrestricted Educational Grant from Salix Pharmaceuticals. April 2015.
Associations Between Lipodystrophy or Antiretroviral Medications and
Cirrhosis in Patients with HIV Infection or HIV/HCV Coinfection »

Study results from Dr. George Ioannou. Does long-term exposure to specific antiretroviral medications or the presence of HALS predispose HIV-infected patients to the development of cirrhosis?
European Journal of Gastroenterology & Hepatology. March 2015.
Proteomics Analysis of Bodily Fluids in Pancreatic Cancer »
Study results from Drs. Sheng Pan, Teresa Brentnall and Ru Chen. Proteomics study of pancreatic cancer using bodily fluids emphasizes biomarker discovery and clinical application, presenting unique prospects and challenges. Fluid proteomics studies to date have provided a wealth of information in revealing proteome alterations associated with pancreatic cancer in various bodily fluids.
Proteomics. March 2015.
Cost Considerations in Implementing a Screening and Surveillance Strategy for Barrett's Esophagus »
Study results from Dr. John Inadomi. There is increasing concern over the rising costs of healthcare leading to debate regarding the use of resources to implement preventive strategies. Oesophageal adenocarcinoma and its precursor, Barrett's oesophagus provides an excellent opportunity to highlight this issue since cancer is uncommon even among individuals with documented Barrett's oesophagus.
Best Practice & Research Clinical Gastroenterology. February 2015.
Molecular Markers Predictive of Chemotherapy Response in Colorectal Cancer »
Study results from Dr. William Grady. Recognition of the molecular heterogeneity of colorectal cancer (CRC) has led to the classification of CRC based on a variety of clinical and molecular characteristics. Although the clinical significance of the majority of these molecular alterations is still being ascertained, it is widely anticipated that these characteristics will improve the accuracy of our ability to determine the prognosis and therapeutic response of CRC patients.
Current Gastroenterology Reports. February 2015.
Dr. Jasmine Zia Among 14 Researchers to Win 2015 UW Innovation Awards »
Congratulations to Dr. Jasmine Zia, one of 14 researchers across the UW campus to receive this year's UW Innovation Awards. Dr. Zia is part of a team of six researchers building tools for use on a mobile device that let patients easily enter data about their habits and behaviors related to a particular health problem. These data will help extend the reach of health care beyond the clinic, making it easier for physicians to make diagnoses and treatment plans.
UW Today. February 2015.
Yuck Factor, Yes, But Stool’s Medical Impact Could Be Huge »
Dr. Christina Surawicz, an early advocate of stool transplants (fecal microbiota transplantation), discusses the procedure's extraordinary success and impact.
UW Health Sciences News Beat. February 2015.
Proteins Assocated with Pancreatic Cancer Survival in Patients with Resectable Pancreatic Ductal Adenocarcinoma »
Study results from Dr. Ru Chen. Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal disease with a dismal prognosis. However, while most patients die within the first year of diagnosis, very rarely, a few patients can survive for >10 years. Better understanding the molecular characteristics of the pancreatic adenocarcinomas from these very-long-term survivors (VLTS) may provide clues for personalized medicine and improve current pancreatic cancer treatment.
Laboratory Investigation. January 2015.
Prevalence and Treatment of Chronic Hepatitis C Virus Infection in the US Department of Veterans Affairs »
A review from Dr. George Ioannou. Chronic hepatitis C virus (HCV) is the most common blood-borne pathogen in the United States. HCV disproportionately affects Veterans Affairs (VA) health-care users: 174,302 HCV-infected veterans were in VA care in 2013, making the VA the world's largest HCV care provider.
Epidemiologic Reviews. January 2015.
Clostridium Difficile Infection: Risk Factors, Diagnosis and Management »
Opinion statement from Dr. Christina Surawicz. Clostridium difficile infection is the leading cause of death due to gastrointestinal infections in the US and is the most common cause of nosocomial diarrhea. The emergence of a hypervirulent strain in the early 2000s has been associated with a dramatic increase in the number and severity of cases in the US, Canada, and several other countries.
Current Treatment Options in Gastroenterology. January 2015.
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