Table 11 -- Approach to Documenting a Family History for Colon Cancer
- Obtain family history two generations up and two generations down from patient

- If a relative has cancer, extend history "back" as far as possible

- For each relative record: age or year of birth, age of death, year and cause of death

- Ask about any cancer diagnosis in relatives, and include: age of diagnosis, primary site(s) of cancer, cancer status (and ages) of children of the relative(s) with cancer

- Identify predisposing environmental factors including: high fat or red meat diet, pelvic radiation, smoking, obesity, alcohol abuse

- Ask about treatment for cancer

- Confirm diagnosis with pathology reports

- Does anyone have:
  • GI tract cancers (colon, stomach, small bowel, pancreas, liver and bile-duct)?
  • Non-GI cancers, specifically brain, endometrial, bladder, ovarian, breast, and testicular cancers?
  • Unusual freckles on the face, hands, feet or genital area?
  • Unusual lumps on the skin (e.g., epidermoid cysts, fibromatosis, desmoid tumors)?
  • Bony lesions (e.g., exostoses, osteomas)?
  • A history of fibrocystic breasts, ovarian cysts, or thyroid disease/cancer?
  • Numerous colonic polyps?
  • Inflammatory bowel disease?
- Ask about genetic disease in general including birth defects, miscarriages, and mental retardation

- Record ethnicity of all four grandparents, and record consanguinity (i.e., parents related as first cousins)

- Note the historian (the person who gave the family history)

- Document the date the pedigree was obtained, and by whom

- Put an arrow to the individual(s) seen at the appointment

- Include a key/legend interpreting pedigree symbols (e.g. shading)