|
Cancer
|
Associated
risk
|
Mean age
at diagnosis
|
Intervention
|
Recommendations
|
|
Colon
|
68-75%
|
45
|
Colonoscopy
|
Begin at age 20-25 years, repeat Q 1-2 years until age 40 and then
yearly *
|
|
Uterine
|
30-40%
|
40-60
|
Transvaginal
ultrasound and/or endometrial biopsy
|
Annually,
beginning at age 25-35 years #
|
|
Stomach
|
20%
|
54
|
Upper
endoscopy
|
If
positive family history of stomach cancer, begin at age 30-35 years,
repeat Q 1-2 years *#
|
|
Hepatobiliary
|
18%
|
66
|
None
|
None
currently
|
|
Urinary
system
|
9-19%
|
56-66
|
Cytology/ultrasound
|
If
positive family history of urinary tract cancers, begin at age 30-35
years, repeat Q 1-2 years *#
|
|
Ovarian
|
<10%
|
45
|
Transvaginal
ultrasound and/or CA-125
|
Annually,
beginning at 25-30 years * #
|
|
Brain
(Turcot Syndrome)
|
|
|
Neurologic
exam
|
Annually,
beginning age 10
|
|
Sebaceous
gland neoplasms (Muir-Torre Syndrome)
|
40%
|
|
Skin
exam
|
Annually
|