Table 3--Summary of three randomized trials supporting efficacy of FOBT in reducing CRC mortality. |
||||||
| Study | Population | Number | FOBT | Frequency | Duration | Mortality Reduction |
| Mandel | Volunteers, Minnesota | 46,551 | Hemoccult, rehydrated | Anuual & Biennial | 13 years | 33% |
| Kronborg | General, Denmark | 61,933 | Hemoccult, non-rehydr. | Biennial | 10 years | 18% |
| Hardcastle | General, U.K. | 150,251 | Hemoccult, non-rehydr. & repeat | Biennial | Median: 7.8 years | 14% |